Background: The oleoresins are compounds that are derived from spices and Essential Oils. These materials have anti-inflammatory and antinociceptive properties. Gum Turpentine is an oleoresin obtained from the Pistacia atlantica genus. It has a long history of traditional medicine in Iran. Hydrogels are three-dimensional, cross-linked networks and water-soluble. They used as carriers for controlled drug release systems for delivery their drug in control inflation. The aim of this study was to evaluate the antinociceptive effect of gum turpentine hydrogel using the hot plate test\nMaterials and methods: PH sensitive hydrogel produced by chitosan deviation and open ring Poly-vinylpyrrolidon (OR-PVP). Turpentine gum & olive oil were purchased at a specific grade. After obtaining hydrogel physicochemical characteristics of Gum turpentine, Antinociceptive effect on mice was investigated by Hot plate test. Statistical analysis was performed by ANOVA and T-test. Turpentine gum compounds were identified by Gas chromatography & GC MS.\nResults: Result showed the best Antinociceptive effect of the formulation is OR-PVP with chitosan equal to 0.4. Formulation with 30% Turpentine gum had a good Antinociceptive effect. Chromatographic studies showed that the main compound among terpenoides was α-pinene followed by β-pinene, 3-carene, limonen, myrtenol, with different amounts in oleoresin.\nConclusions: This study showed that the ability of the turpentine gum hydrogel is a good product for release oleoresins, because reduce inflammation and pain.
Background: Breast cancer is the second leading cause of cancer death among women. One in eight women will be diagnosed with breast cancer in their life period .There are several risk factors for progress of carcinogen cell. Zinc and lead have crucial role in oxidative stress and changes in their level can enhance progress of carcinogen cells. The aim of this study is to discover the level of zinc and lead in plasma of breast cancer patients. \nMaterials and methods: This was a cross sectional study designed in Imam Hospital of Sari located in the north of Iran. One hundred patients with breast carcinoma diagnosis was confirmed by pathological samples and the results were compared with standard values and amount of these elements was observed in the blood by atomic absorption. \nResults: Zinc plasma level in patients was found to be 50.59+4.72 (μg/dL) with p value of p=0.003 which is lower than standard value (80 μg/dL). On the other hand, the plasma lead level was identified to be 6.24+1.173(μg/dL) in patients and zero in the standard value. \nConclusion: According to the observation, breast cancer patients had a higher lead level than standard value and lower zinc level. Zinc acts as an important free-radical scavenger to protect cells and deficiency of that can increases progress of carcinogen cells. Therefore, use of trace elements and also the chelators of heavy metals are necessary to prevent breast cancer in high risk individuals.
Este trabajo propone un modelo de crecimiento tumoral basado en una difusión estocástica Gompertz de tipo no homogéneo, cuyo coeficiente drift depende de dos funciones de tiempo que influyen en el comportamiento dinámico del modelo, y que puede ser interpretado en el contexto del tipo de crecimiento celular. La primera de estas funciones temporales es un factor de terapia inmunológica endógeno, y la segunda es un factor de terapia exógeno que modela la dinámica de un tratamiento controlable externamente sobre el crecimiento tumoral.\nSe presenta un estudio computacional, para el modelo descrito por El Kettani et al. (2014), con el objetivo mostrar la interrelación entre los parámetros internos del proceso de difusión (coeficiente de decaimiento del efecto terapéutico endógeno y las ponderaciones ligadas a cada tipo de las terapias externas consideradas) y el coeficiente de difusión global del modelo, aplicado al crecimiento celular del cáncer de pulmón de células no pequeñas. Todo ello, a partir de las características del modelo de la ecuación diferencial de Itô correspondiente, obteniendo explícitamente la expresión de las funciones tendencias.
Fluoride ion (or simply fluoride) is a hugely abundant element on Earth which is a naturally occurring compound derived from fluorine . Fluoride is characterized by its small radius and its great tendency to behave as a ligand . Fluoride constitutes a large number of different organic and inorganic compounds in soil, rocks, air, plants and animals. It is found in surface and groundwater as an almost completely dissociated fluoride ion . This presence is usually related to geochemical reactions or anthropogenic activities for example; the disposal of industrial wastewater . The natural amount of fluoride in groundwater depends on the geological, chemical, and physical characteristics of the aquifer, the availability and solubility of fluoride minerals, rate of flowing water, temperature, pH, and concentration of other chemicals like calcium and bicarbonate ions . Many studies reveal that drinking water is the major source of fluoride daily intake . Fluoride is an essential trace element for animals and humans and it makes water hazardous when present in excess. World Health Organization (WHO) has specified the tolerance limit of fluoride content of drinking water at 1.5 mg/L . Excessive fluoride intake causes adverse health effects such as crippling skeletal fluorosis that is a significant cause of morbidity in a number of regions of the world. Fluoride is also toxic and its accumulation causes harm of brain/mind development of children . Studies have shown that the exposure to high doses of fluoride leads to Kidney diseases .
Ultrasound has attracted interest in food engineering because of its promising effects on conservation. This can be applied to develop processes aimed at improving quality and safety. The objective of this work was to explore the effects of high intensity ultrasound (US) on the color profile, changes in surface myoglobin, as well as on shear force. It was performed on the Longissimus thoracis muscle of meat pork cut into 3x2x3 cm plates, which were subsequently US at 40 kHz for 5, 10 and 15 min. The results were analyzed in Minitab 16.0.1 using ANOVA (P < 0.05) and Tukey\
A survey was conducted in Obuasi municipality in Adansi North to assess manure production, management and utilization. Structured questionnaires and personal observations were used as tool (research method). In all twenty samples (poultry farmers) were conveniently selected using convenience sampling technique.\\nThe collection of the data took six weeks, thus from 16th December, 2011 to 27th December, 2012. Data obtained were analysed using statistical Package for Social Sciences (SPSS) computer software. Descriptive statistics namely means, frequencies, percentages and tabulations were used to determine relationships between variables.\\nThe research revealed that 75% of poultry farmers in Obuasi municipality produce manure/bedding material as the major waste and 25% of the farmers produce wasted feed/broken eggs. The research further revealed that 85% of the poultry farmers in Obuasi municipality store their waste in sacks and 15% of them store in outside structures. Again, it can be observed from the study that 35% of the farmers apply the waste generated in their crop farms to serve as organic fertilizer. The research also revealed that 20% of the farmers apply the manure in their fish ponds. This serves as feed for the fishes and fertilizer to the phytoplankton and other primary productivity. Lastly, the research revealed that 30% of the poultry farms are 10m close to the nearness residential area. 15% of the farms are 20m close to the nearness residential area and 25% of them are also 30m close to residential areas.
This is an observation that, by its nature, can be very interesting to researchers involved in all aspects of headache and related pain, including clinical practice and pain management.\\n\\nOur patient presented clinical episodes of sudden visual alterations compatible with migraine with aura without pain. The process could be related to an episode that patient suffered in the childhood and to the malformations in the circle of Willis, the vertebral artery hypoplasia, or both. \\n\\nAn early angiographic study with migraine with aura, with or without headache, could contribute to the identification of structural abnormalities in the cerebral vessels and help us to understand the hemodynamic mechanisms that occur in patients with migraine.\\n\\nIn this sense, these studies allow us to propose preventive therapeutic approaches that reduce or correct the personal susceptibility. Furthermore, as pointed out by other authors, angiographic studies, could help us to understand the possible mechanisms that underlie migraine with aura and their relation to subclinical stroke.